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705 Hazard Communication Program
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GHS Safety Data Sheet Sections

Section 11: Toxicological Information

This section identifies toxicological and health effects information or indicates that such data are not available. The required information consists of:

  • Information on the likely routes of exposure (inhalation, ingestion, skin and eye contact). The SDS should indicate if the information is unknown.
  • Description of the delayed, immediate, or chronic effects from short- and long-term exposure.
  • The numerical measures of toxicity (e.g., acute toxicity estimates such as the LD50 (median lethal dose)) - the estimated amount [of a substance] expected to kill 50% of test animals in a single dose.
  • Description of the symptoms. This description includes the symptoms associated with exposure to the chemical including symptoms from the lowest to the most severe exposure.
  • Indication of whether the chemical is listed in the National Toxicology Program (NTP) Report on Carcinogens (latest edition) or has been found to be a potential carcinogen in the International Agency for Research on Cancer (IARC) Monographs (latest editions) or found to be a potential carcinogen by OSHA.

Section 12. Ecological Information

This section provides information to evaluate the environmental impact of the chemical(s) if it were released to the environment. The information may include:

  • Data from toxicity tests performed on aquatic and/or terrestrial organisms, where available (e.g., acute or chronic aquatic toxicity data for fish, algae, crustaceans, and other plants; toxicity data on birds, bees, plants).
  • Whether there is a potential for the chemical to persist and degrade in the environment either through biodegradation or other processes, such as oxidation or hydrolysis.
  • Results of tests of bioaccumulation potential, making reference to the octanol-water partition coefficient (Kow) and the bioconcentration factor (BCF), where available.
  • The potential for a substance to move from the soil to the groundwater (indicate results from adsorption studies or leaching studies).
  • Other adverse effects (e.g., environmental fate, ozone layer depletion potential, photochemical ozone creation potential, endocrine disrupting potential, and/or global warming potential).

Section 13. Disposal Considerations

This section provides guidance on proper disposal practices, recycling or reclamation of the chemical(s) or its container, and safe handling practices. To minimize exposure, this section should also refer the reader to Section 8 (Exposure Controls/Personal Protection) of the SDS. The information may include:

  • Description of appropriate disposal containers to use.
  • Recommendations of appropriate disposal methods to employ.
  • Description of the physical and chemical properties that may affect disposal activities.
  • Language discouraging sewage disposal.
  • Any special precautions for landfills or incineration activities.

Knowledge Check Choose the best answer for the question.

4-6. Which SDS section contains special precautions for landfills or incineration activities?